The treatment of gastrinomas involves a combination of approaches: 1. Surgical Resection - The primary treatment for localized gastrinomas. 2. Proton Pump Inhibitors (PPIs) - Medications like omeprazole are used to control gastric acid secretion. 3. Somatostatin Analogues - Drugs such as octreotide can help control symptoms and slow tumor growth. 4. Chemotherapy - Used in advanced cases where surgery is not an option.