How are IDCs Differentiated from Other Dendritic Cells?
IDCs can be differentiated from other dendritic cells by their specific location and their role in the immune system. While other dendritic cells, such as Langerhans cells, are found in the epidermis and mucosal surfaces, IDCs are localized to lymphoid tissues. Additionally, IDCs have a unique capacity for activating naive T-cells, a function that is less pronounced in other dendritic cell subsets.