How do Type I Alveolar Cells Interact with Other Cells?
Type I alveolar cells work closely with Type II alveolar cells (Type II pneumocytes), which secrete surfactant to reduce surface tension within the alveoli and prevent their collapse. Type II cells can also differentiate into Type I cells, aiding in the repair and regeneration of the alveolar epithelium. Moreover, Type I cells are in close contact with alveolar macrophages, which patrol the alveolar surface and phagocytize debris and pathogens.
