Chemotactic factors work through a process known as chemotaxis, where cells move in response to a chemical gradient. Cells have specialized receptors on their surfaces that detect these gradients and trigger intracellular signaling pathways. This leads to cytoskeletal rearrangements and directed movement. Common chemotactic factors include cytokines, chemokines, and growth factors. Examples are interleukins, tumor necrosis factor (TNF), and granulocyte-macrophage colony-stimulating factor (GM-CSF).