How are Chemotactic Factors Involved in Tissue Repair?

Chemotactic factors also play a crucial role in tissue repair and regeneration. After an injury, factors such as platelet-derived growth factor (PDGF) and transforming growth factor-beta (TGF-β) are released. These factors attract fibroblasts and endothelial cells to the wound site, promoting new tissue formation and blood vessel development, a process known as angiogenesis. Understanding these mechanisms can provide insights into improving wound healing and developing therapies for chronic wounds.