Bone remodeling is a continuous process where old bone is replaced by new bone. Bone pathologies can disrupt this balance:
In osteoporosis, the rate of bone resorption exceeds bone formation, leading to weakened bones. Osteomalacia impairs the mineralization process, resulting in soft and weak bones. Paget's Disease causes excessive and disorganized bone remodeling, leading to structurally unsound bones. In osteomyelitis, inflammation and infection interfere with normal bone remodeling, causing bone destruction and potential deformities. Bone tumors can disrupt normal bone architecture and remodeling, either through direct invasion or by inducing abnormal bone formation.
