Strategies to mitigate overdiagnosis include: 1. Refined Screening Guidelines: Developing more precise guidelines for screening can help reduce the detection of indolent conditions. For example, adjusting the frequency or age range for screening programs. 2. Risk Stratification: Incorporating risk stratification models that consider patient-specific factors such as age, genetics, and lifestyle can help identify which patients are more likely to benefit from further investigation and treatment. 3. Second Opinions: Seeking a second opinion from another pathologist can help ensure that the diagnosis is accurate and that a more conservative approach may be appropriate.
