Interpretation variability can be measured using several methods:
1. Interobserver Agreement: This measures the consistency of interpretations between different observers. Common statistical tools for this purpose include Cohen's kappa and intraclass correlation coefficient (ICC). 2. Intraobserver Agreement: This measures the consistency of interpretations by the same observer at different times. It is crucial for assessing the reliability of individual pathologists. 3. Proficiency Testing: Regular proficiency testing and external quality assessments can help measure and improve consistency among pathologists.