Identification of architectural disturbance involves several techniques:
Histological Staining: Techniques like Hematoxylin and Eosin (H&E) staining highlight tissue and cellular structures, allowing for the visualization of architectural disruptions. Immunohistochemistry (IHC): This technique uses antibodies to detect specific proteins, which can reveal changes in tissue organization and cell composition. Microscopy: Light and electron microscopy provide detailed images of tissue architecture, facilitating the identification of abnormalities. Digital Pathology: Advanced imaging and computational tools aid in the analysis of tissue architecture, enhancing diagnostic accuracy.