These modifications are studied using various histological techniques, including:
Histochemical Staining: Special stains can highlight specific components of cells and tissues, aiding in the identification of pathological changes. Immunohistochemistry: This technique uses antibodies to detect specific proteins, providing insights into cellular function and pathology. Electron Microscopy: Offers high-resolution images to study ultrastructural changes in cells and tissues. Molecular Techniques: Methods such as PCR and in situ hybridization can detect genetic and molecular changes underlying histological modifications.