How are Oncoprotein Isoforms Detected in Histology?
In histology, the detection of oncoprotein isoforms typically involves immunohistochemistry (IHC) and Western blotting. IHC can localize specific protein isoforms within tissue sections using antibodies. Western blotting can distinguish between different isoforms based on their molecular weight. These techniques help in identifying the presence and distribution of oncoprotein isoforms in cancer tissues.
