What are the Histological Features of Amastigote Nests?
In histological sections, amastigote nests appear as clusters of small, round to oval organisms within the cytoplasm of macrophages or other host cells. Each amastigote measures approximately 2-4 micrometers in diameter and contains a nucleus and a rod-shaped kinetoplast. The surrounding tissue may show signs of inflammation, such as infiltration by lymphocytes, plasma cells, and other inflammatory cells.