leydig cells

How are Leydig Cells Identified in Histological Studies?

In histological studies, Leydig cells can be identified by their distinctive morphology and the presence of specific markers. Immunohistochemistry techniques utilizing antibodies against enzymes involved in steroidogenesis, such as 3β-hydroxysteroid dehydrogenase (3β-HSD), can help in their identification. Additionally, electron microscopy can provide detailed insights into their ultrastructural features, such as the abundance of SER and mitochondria with tubular cristae.

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