Histopathological variants are identified through various diagnostic techniques, including:
- Microscopy: Light microscopy and electron microscopy are fundamental tools for examining tissue samples. Special stains and dyes are used to highlight specific cellular components. - Immunohistochemistry: This technique involves the use of antibodies to detect specific antigens in tissue sections. It helps in identifying the origin of cells and the presence of particular proteins. - Molecular Pathology: Techniques such as PCR and FISH are used to detect genetic alterations and chromosomal abnormalities in tissues. These methods are essential for diagnosing certain cancers and genetic disorders.