In histology, early endosomes can be studied using immunohistochemistry and electron microscopy. Antibodies against specific endosomal markers such as EEA1 (Early Endosome Antigen 1) or Rab5 are commonly used to visualize early endosomes in tissue sections. Fluorescent tagging and confocal microscopy also allow for the detailed examination of endosomal dynamics in living cells. These techniques provide insights into the distribution, morphology, and function of early endosomes in different cell types and tissues.