Are there any therapeutic implications related to PINK1?
Given its role in mitochondrial quality control, PINK1 is a promising target for therapeutic interventions aimed at treating neurodegenerative diseases. Potential therapies could involve upregulating PINK1 activity or mimicking its function to enhance mitophagy and prevent the accumulation of damaged mitochondria. Research is ongoing to develop small molecules, gene therapies, and other strategies to modulate PINK1 activity.