Are There Any Clinical Applications of HLA Typing?
Yes, HLA typing has several clinical applications:
- Bone Marrow Transplantation: Matching HLAs between donor and recipient is crucial to avoid GVHD. - Paternity Testing: HLA typing can be used to determine biological relationships. - Disease Prediction: Certain HLA types can predict susceptibility to autoimmune diseases. - Pharmacogenomics: HLA typing can predict adverse drug reactions, such as Stevens-Johnson syndrome.
