poly l lysine

Why is Poly L Lysine Used in Histology?

In histological applications, poly L lysine is primarily used to improve the adherence of tissue sections to glass slides. This is particularly important during processes that involve multiple washing steps, such as staining and immunohistochemical labeling, where poorly adhered sections may detach. The polymer binds to the glass surface and provides a positively charged substrate that attracts the negatively charged components of the tissue, thus enhancing adherence.

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