MMEJ is crucial for several reasons: 1. Backup Repair Pathway: It acts as a backup when other DSB repair mechanisms fail or are unavailable. 2. Genetic Stability: It contributes to the genetic stability of cells and tissues by repairing DSBs, thus preventing cell death. 3. Cancer Research: Defects in MMEJ are often linked to cancer, making it a target for cancer research and potential therapies.
