bcl 2 family of proteins

What is the Bcl-2 Family?

The Bcl-2 family consists of proteins that share one or more of four characteristic Bcl-2 Homology (BH) domains. These proteins are categorized into three main groups:
Anti-apoptotic proteins (e.g., Bcl-2, Bcl-xL, Mcl-1)
Pro-apoptotic effector proteins (e.g., Bax, Bak)
Pro-apoptotic BH3-only proteins (e.g., Bid, Bad, Bim)

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