Why is HER2 Status Important in Clinical Practice?
Determining the HER2 status of a tumor is crucial for guiding treatment strategies. HER2-positive cancers tend to be more aggressive but can respond well to targeted therapies such as trastuzumab (Herceptin), pertuzumab, and lapatinib. These therapies specifically target the HER2 receptor, inhibiting its signaling pathways and thereby reducing tumor growth.
