In the context of histology, understanding rRNAs is crucial for a few reasons. Firstly, rRNAs are abundant in cells that are actively synthesizing proteins, which can be indicative of specific cell types or states of activity. For example, cells in the pancreatic acini or neurons often show prominent nucleoli due to high rRNA synthesis. Secondly, rRNAs are used as markers in various histological techniques, such as in situ hybridization, to study gene expression patterns.