Why are Gli Transcription Factors Important in Histology?
Gli transcription factors are pivotal in histology because they regulate the expression of genes involved in cell proliferation, differentiation, and apoptosis. Aberrant Gli signaling is implicated in various diseases, including cancers such as basal cell carcinoma and medulloblastoma. Understanding the role of these factors in normal and diseased tissues can provide insights into the mechanisms underlying these conditions.
