What is the Histological Basis of Corneal Cross-Linking?
The cornea is composed primarily of collagen fibers organized in a lattice structure, crucial for its transparency and refractive properties. In conditions like keratoconus, the integrity of this lattice is compromised. CXL involves the application of riboflavin (vitamin B2) followed by ultraviolet-A (UVA) light exposure. Histologically, this process enhances the cross-linking of collagen fibers, thereby increasing the cornea's stiffness and resistance to deformation.
