Which Conditions Are Associated with Excitotoxicity?
Excitotoxicity is implicated in a range of neurological conditions, including stroke, traumatic brain injury (TBI), Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). During a stroke, for instance, the lack of oxygen and glucose supply leads to energy failure, impairing the cells' ability to regulate ion gradients, thereby promoting excitotoxicity.
