Transglutaminases are found throughout the body, but their distribution varies depending on the specific type. For instance, tissue transglutaminase (TG2) is ubiquitously expressed and is involved in multiple cellular processes. Another type, factor XIII, is primarily found in the blood and is essential for blood clot stabilization. Other members of the transglutaminase family are localized in the skin, hair follicles, and even in the nervous system.
