What is the Role of Transglutaminases in Histology?
In histology, transglutaminases play a crucial role in the structural integrity and function of tissues. They are involved in the cross-linking of proteins, which helps to stabilize the extracellular matrix and cell membranes. This cross-linking is essential for maintaining the mechanical strength of tissues and for processes such as wound healing and keratinization. Additionally, transglutaminases are involved in the formation of the cornified cell envelope in the skin, which acts as a barrier to protect underlying tissues.