IGFs are ubiquitous and can be found in various tissues throughout the body. In the context of histology, they are particularly significant in tissues such as skeletal muscle, bone, and cartilage. In skeletal muscle, IGFs are involved in muscle growth and regeneration. In bones, they promote both bone formation by osteoblasts and bone resorption by osteoclasts. In cartilage, IGFs are essential for chondrocyte proliferation and matrix production.
