1. Ribosomes: Palade identified and described ribosomes, the cellular structures responsible for protein synthesis. His work showed that ribosomes are the sites where genetic information is translated into proteins.
2. Endoplasmic Reticulum: He elucidated the role of the rough endoplasmic reticulum (rER) in the synthesis of secretory proteins and its relationship with ribosomes.
3. Cellular Transport: Palade discovered the pathway by which proteins are synthesized in the rER, processed in the Golgi apparatus, and transported in vesicles to their final destinations.