toxic insults

What Toxins Commonly Cause Histological Changes?

Several toxins are known to cause specific histological changes:
- Alcohol: Chronic alcohol exposure leads to fatty liver, where hepatocytes appear swollen with fat droplets.
- Carbon Tetrachloride: Causes fatty change and centrilobular necrosis in the liver.
- Lead: Results in basophilic stippling of erythrocytes and renal tubular damage.
- Mercury: Leads to disruption of the renal proximal tubules, showing cellular degeneration and necrosis.

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