Several toxins are known to cause specific histological changes:
- Alcohol: Chronic alcohol exposure leads to fatty liver, where hepatocytes appear swollen with fat droplets. - Carbon Tetrachloride: Causes fatty change and centrilobular necrosis in the liver. - Lead: Results in basophilic stippling of erythrocytes and renal tubular damage. - Mercury: Leads to disruption of the renal proximal tubules, showing cellular degeneration and necrosis.