When examining skin biopsy slides, pathologists look for several key features: - Epidermal Changes: Any abnormalities in the layers of the epidermis, such as hyperkeratosis, parakeratosis, or acanthosis. - Dermal Changes: Inflammatory infiltrates, fibrosis, or vascular changes in the dermis. - Cellular Atypia: Abnormal cells that may indicate malignancy. - Subcutaneous Tissue: Changes in the fat layer beneath the dermis, such as panniculitis.
