Several techniques employ reporter genes to investigate cellular and tissue-level phenomena. These include:
Transgenic animal models: Animals engineered to express a reporter gene under the control of specific promoters help in studying gene function and regulation in vivo. In situ hybridization: This technique can be combined with reporter genes to visualize the localization of specific mRNA within tissues. Immunohistochemistry: Reporter gene products can be detected using antibodies, allowing for precise localization within histological sections.