What Techniques in Histology are Used for Drug Target Identification?
Several histological techniques are employed to identify and validate drug targets:
Immunohistochemistry (IHC): This technique uses antibodies to detect specific antigens in tissue sections, allowing for the visualization of protein expression patterns. In Situ Hybridization (ISH): Used to detect specific nucleic acid sequences within tissues, providing information on gene expression. Histopathology: The examination of diseased tissues can reveal morphological changes associated with specific diseases, aiding in target identification. Fluorescence Microscopy: Allows for the visualization of fluorescently labeled molecules within cells and tissues, providing insights into cellular functions and interactions.
