Several techniques are employed to enhance sensitivity in histology:
Immunohistochemistry (IHC): Utilizes antibodies to detect specific antigens in tissue samples, providing high sensitivity for protein detection. Fluorescence Microscopy: Uses fluorescent dyes and markers to visualize structures and molecules with high sensitivity and specificity. Polymerase Chain Reaction (PCR): Amplifies DNA sequences, allowing for the detection of even small amounts of genetic material in tissue samples. In Situ Hybridization (ISH): Detects specific nucleic acid sequences within tissues, providing high sensitivity for gene expression studies.