infectious disease studies

What Techniques are Used in Histology for Infectious Disease Detection?

Several histological techniques are used to detect infectious diseases:
Hematoxylin and Eosin (H&E) Staining: The most common staining technique, it helps visualize general tissue structure and identify abnormalities.
Special Stains: Techniques like Gram stain, Ziehl-Neelsen stain, and Giemsa stain are used to identify specific types of bacteria, mycobacteria, and parasites, respectively.
Immunohistochemistry (IHC): Uses antibodies to detect specific antigens in tissues, allowing precise identification of pathogens.
In Situ Hybridization (ISH): Detects specific nucleic acid sequences within tissues, useful for identifying viral infections.
Electron Microscopy: Provides detailed images of ultrastructural changes in tissues caused by infections.

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