What Role Does Immunohistochemistry Play in Subtyping?
Immunohistochemistry (IHC) is a technique used to detect specific proteins in tissues using antibodies. It plays a crucial role in histological subtyping by allowing pathologists to:
Identify specific markers that differentiate between subtypes. Assess the expression of proteins that might indicate the aggressiveness of a tumor. Guide treatment decisions based on marker expression, such as HER2 in breast cancer.
