Disruption in cell polarity is linked to various diseases. For instance:
1. Cancer: Loss of polarity is a hallmark of cancerous cells, leading to uncontrolled growth and metastasis. 2. Polycystic Kidney Disease: Polarity defects in renal epithelial cells result in cyst formation. 3. Neurological Disorders: Abnormal cell polarity can affect brain development, leading to conditions such as autism and epilepsy.
