What Role Does ATP Play in Cross Bridge Formation?
ATP plays a crucial role in the cross bridge cycle. First, ATP binds to the myosin head, causing it to detach from the actin filament. The hydrolysis of ATP to ADP and inorganic phosphate (Pi) provides the energy required for the myosin head to return to its high-energy configuration. When the myosin head rebinds to actin, it releases the ADP and Pi, resulting in a power stroke that pulls the actin filament towards the center of the sarcomere, leading to muscle contraction.
