Staining is another crucial aspect of histology that relies on specific chemical interactions. Stains are chemical dyes that bind selectively to different tissue components, enhancing contrast and allowing for detailed visualization under the microscope. Hematoxylin and eosin (H&E) staining is one of the most common techniques. Hematoxylin stains cell nuclei blue due to its affinity for DNA, while eosin stains the cytoplasm and extracellular matrix pink.