Several methods are employed to preserve tissue integrity, including:
Fixation: The most common method, fixation involves using chemical agents like formaldehyde to cross-link proteins and halt biological processes. Freezing: Rapid freezing of tissues using cryopreservation techniques preserves the tissue architecture and enzyme activity. Dehydration: Gradual removal of water using alcohols, often followed by clearing and embedding in paraffin. Embedding: Involves infiltrating tissues with paraffin or resin to provide support for sectioning.