Composite scaffolds typically combine natural and synthetic materials to leverage the advantages of both. Common natural materials include collagen, chitosan, and gelatin, which are biocompatible and promote cell adhesion. Synthetic materials like polylactic acid (PLA), polyglycolic acid (PGA), and polycaprolactone (PCL) provide mechanical strength and can be tailored to degrade at specific rates. The combination of these materials results in scaffolds that can be customized for various tissue engineering applications.