What Makes TALENs Unique Compared to Other Genome Editing Tools?
While CRISPR-Cas9 has gained widespread popularity, TALENs offer unique advantages. They tend to have higher specificity due to the longer recognition sites, reducing off-target effects. TALENs can also target a wider range of genomic sequences, including those that are difficult for CRISPR-Cas9 systems to access. Additionally, TALENs do not require an adjacent protospacer adjacent motif (PAM) sequence, making them more versatile for certain applications.
