What are the Common Pathological Conditions Associated with Langhans Giant Cells?
Langhans giant cells are associated with several pathological conditions, most notably:
- Tuberculosis: They are a hallmark feature in the granulomas formed during this infection. - Sarcoidosis: Another granulomatous disease where these cells are frequently observed. - Leprosy: Certain types of leprosy, particularly tuberculoid leprosy, show the presence of these giant cells. - Syphilis: In tertiary syphilis, Langhans giant cells can be found within gummas. - Chronic Granulomatous Disease: This genetic disorder, which affects phagocyte function, can also show these cells in granulomatous lesions.
