Inclusions serve various roles ranging from storage to indicators of cellular health or disease:
1. Storage: Substances like glycogen and lipid droplets act as energy reserves. 2. Diagnostic Markers: The presence of certain inclusions can aid in diagnosing diseases. For instance, the accumulation of hemosiderin can indicate conditions like hemochromatosis. 3. Cellular Aging: The build-up of pigments like lipofuscin can be an indicator of cellular aging and oxidative stress.