What is the Role of Histology in Understanding Autoimmune Diseases?
Autoimmune diseases occur when the immune system mistakenly attacks the body's own tissues. Histology provides insights into the pathological changes associated with autoimmune conditions. For instance, in rheumatoid arthritis, histological examination of joint tissues reveals the presence of immune cell infiltration, synovial hyperplasia, and cartilage destruction. Similarly, in lupus erythematosus, skin biopsies show immune complex deposition and inflammatory cell infiltration.
