The DPY19L2 protein is essential for the proper anchoring of the acrosome to the nucleus of the sperm cell. The acrosome is a cap-like structure that contains enzymes necessary for the sperm to penetrate an egg. Mutations in the DPY19L2 gene can lead to a condition known as globozoospermia, where the sperm cells have round heads and lack acrosomes, resulting in infertility.
