What are the Clinical Implications of DPY19L2 Mutations?
Mutations in DPY19L2 are a major cause of globozoospermia, which is a rare but severe form of male infertility. Couples affected by this condition often seek assisted reproductive technologies (ART) such as Intracytoplasmic Sperm Injection (ICSI) to achieve pregnancy. Genetic testing for DPY19L2 mutations can provide a definitive diagnosis and help guide treatment options.
