dopachrome tautomerase

What is the Role of Dopachrome Tautomerase in Melanogenesis?


In the complex process of melanin biosynthesis, DCT facilitates a critical step by converting dopachrome to DHICA, a precursor that leads to the production of eumelanin, a type of melanin that provides black and brown pigmentation. This step is essential not only for determining the type of melanin produced but also for influencing the overall efficiency and regulation of melanin production. The presence of DCT ensures the proper balance between eumelanin and pheomelanin, contributing to the wide range of human skin and hair colors.

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