Histological techniques are pivotal in studying dystrophin. Immunohistochemistry (IHC) is commonly used to detect dystrophin within muscle tissues. This involves using specific antibodies that bind to dystrophin, allowing for its visualization under a microscope. Fluorescence microscopy can also be employed to observe dystrophin distribution and localization within muscle fibers. These techniques help in diagnosing dystrophin-related disorders and in understanding the molecular pathology of these diseases.