What is the Importance of Osmolality in Histology?
Osmolality refers to the concentration of solutes in a solution and is crucial for maintaining the integrity of cells and tissues during histological procedures. An imbalance in osmolality can cause cells to swell or shrink, leading to artifacts in tissue morphology. Therefore, solutions used in histology, including fixatives and staining reagents, are carefully prepared to match the osmolality of the tissues being studied.
